Regulatory regions in natural transposable element insertions drive interindividual differences in response to immune challenges in Drosophila.

Abstract excerpt

BACKGROUND: Variation in gene expression underlies interindividual variability in relevant traits including immune response. However, the genetic variation responsible for these gene expression changes remains largely unknown. Among the non-coding variants that could be relevant, transposable element insertions are promising candidates as they have been shown to be a rich and diverse source of cis-regulatory...

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