Article
Inferring predominant pathways in cellular models of breast cancer using limited sample proteomic profiling.
BMC cancer - 15 Jun 2010
Kulkarni Yogesh M, Suarez Vivian, Klinke David J
Abstract excerpt
BACKGROUND: Molecularly targeted drugs inhibit aberrant signaling within oncogenic pathways. Identifying the predominant pathways at work within a tumor is a key step towards tailoring therapies to the patient. Clinical samples pose significant challenges for proteomic profiling, an attractive approach for identifying predominant pathways. The objective of this study was to determine if information obtained from...
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