Association between an intronic apolipoprotein E polymorphism and bone mineral density in Singaporean Chinese females.

doi:10.1016/j.bone.2010.05.028

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Association between an intronic apolipoprotein E polymorphism and bone mineral density in Singaporean Chinese females.

Bone - 1 Sept 2010

Tong Terry Y Y, Yong Rita Y Y, Goh Victor H H, Liang Shen, Chong Alicia P L, Mok Helen P P, Yong Eu Leong, Yap Eric P H, Moochhala Shabbir

Abstract excerpt

INTRODUCTION: Apolipoprotein E (ApoE) is implicated in the pathogenesis of osteoporosis. OBJECTIVE: To investigate possible association of the non-classical APOE gene +113C/G (rs440446) intron 1 enhancer polymorphism with bone mineral density (BMD) in a homogeneous Chinese population in Singapore. METHODS: A total of 655 volunteers, males and females, aged between 31 and 72 years, from the public participated....

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PMID: 20546958
DOI: 10.1016/j.bone.2010.05.028

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APOE

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