Article
The prevalence of Apo E4 genotype and its relationship to bone mineral density in Hong Kong Chinese.
Journal of bone and mineral metabolism - 1 Jan 2005
Wong Samuel Yeung Shan, Lau Edith Ming Chu, Li Martin, Chung Tiffany, Sham Aprille, Woo Jean
Abstract excerpt
Apolipoprotein E (Apo E) polymorphism has been implicated in many chronic diseases, including Alzheimer disease and osteoporosis. Significant association of the Apo E4 allele to low bone mineral density (BMD) has been repeatedly reported. We here examined the Apo E genotype frequencies in the Chinese population (n = 692) and its relationship to BMD. A significantly lower frequency (a prevalence of 7%) of the E4...
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