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Article

Identification of population substructure among Jews using STR markers and dependence on reference populations included.

BMC genetics - 14 Jun 2010

Listman Jennifer B, Hasin Deborah, Kranzler Henry R, Malison Robert T, Mutirangura Apiwat, Sughondhabirom Atapol, Aharonovich Efrat, Spivak Baruch, Gelernter Joel

Abstract excerpt

BACKGROUND: Detecting population substructure is a critical issue for association studies of health behaviors and other traits. Whether inherent in the population or an artifact of marker choice, determining aspects of a population's genetic history as potential sources of substructure can aid in design of future genetic studies. Jewish populations, among which association studies are often conducted, have a...

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PMID: 20546593
DOI: 10.1186/1471-2156-11-48
PMCID: PMC2896335

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