Article
The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana.
The Plant cell - 1 Jun 2010
Isono Erika, Katsiarimpa Anthi, Müller Isabel Karin, Anzenberger Franziska, Stierhof York-Dieter, Geldner Niko, Chory Joanne, Schwechheimer Claus
Abstract excerpt
Ubiquitination, deubiquitination, and the formation of specific ubiquitin chain topologies have been implicated in various cellular processes. Little is known, however, about the role of ubiquitin in the development of cellular organelles. Here, we identify and characterize the deubiquitinating enzyme AMSH3 from Arabidopsis thaliana. AMSH3 hydrolyzes K48- and K63-linked ubiquitin chains in vitro and accumulates...
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