Article
Internalization and vacuolar targeting of the brassinosteroid hormone receptor BRI1 are regulated by ubiquitination.
Nature communications - 21 Jan 2015
Martins Sara, Dohmann Esther M N, Cayrel Anne, Johnson Alexander, Fischer Wolfgang, Pojer Florence, Satiat-Jeunemaître Béatrice, Jaillais Yvon, Chory Joanne, Geldner Niko, Vert Grégory
Abstract excerpt
Brassinosteroids are plant steroid hormones that control many aspects of plant growth and development, and are perceived at the cell surface by the plasma membrane-localized receptor kinase BRI1. Here we show that BRI1 is post-translationally modified by K63 polyubiquitin chains in vivo. Using both artificial ubiquitination of BRI1 and generation of an ubiquitination-defective BRI1 mutant form, we demonstrate...
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