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Regulation of blood–testis barrier dynamics by TGF-β3 is a Cdc42-dependent protein trafficking event

7 Jun 2010

Abstract excerpt

In the testis, the blood-testis barrier (BTB) is constituted by specialized junctions between adjacent Sertoli cells in the seminiferous epithelium near the basement membrane. Although the BTB is one of the tightest blood-tissue barriers in the mammalian body, it undergoes extensive restructuring at stage VIII of the seminiferous epithelial cycle to facilitate the transit of preleptotene spermatocytes. Thus,...

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PMID: 20534521
DOI: 10.1073/pnas.1001077107

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