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TGF-β3 Regulates the Blood-Testis Barrier Dynamics via the p38 Mitogen Activated Protein (MAP) Kinase Pathway: An in Vivo Study

15 Mar 2003

Abstract excerpt

Recent studies using Sertoli cells cultured in vitro to permit tight junction (TJ) assembly have shown that TJ dynamics are regulated, at least in part, by TGF-beta3 via the p38 mitogen activated protein (MAP) kinase pathway. This in turn regulates the production of occludin, a TJ-integral membrane protein, by Sertoli cells. Yet it is not known if this pathways is used by Sertoli cells to regulate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12639893
DOI: 10.1210/en.2002-0211

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