Article
A single low dose of dendritic cells modified with lentivirus containing a truncated neu gene can effectively suppress neu-overexpressing tumors.
The journal of gene medicine - 1 Jul 2010
Li Gong-Bo, Lu Guang-Xiu
Abstract excerpt
BACKGROUND: Several types of viral-transduced HER2/neu-modified dendritic cells (DC(HER2/neu)) have been used for preventing and/or treating HER2/neu-overexpressing tumors. However, to date, lentivirus has not been used to generate HER2/neu-modified DCs. METHODS: In the present study, we used rec...
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