Article
ErbB2 genetic cancer vaccine in nonhuman primates: relevance of single nucleotide polymorphisms.
Human gene therapy - 1 Mar 2009
Fattori Elena, Aurisicchio Luigi, Zampaglione Immacolata, Arcuri Mirko, Cappelletti Manuela, Cipriani Barbara, Mennuni Carmela, Calvaruso Francesco, Nuzzo Maurizio, Ciliberto Gennaro, Monaci Paolo, La Monica Nicola
Abstract excerpt
Aberrant Her2/neu expression is associated with the development of epithelial-derived human carcinomas and for this reason it is considered a good target for immunologic intervention. To define methods to circumvent immunologic tolerance and to elicit immunity against the Her2/neu tumor-associate...
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