Article
Apolipoprotein E polymorphism: A new genetic marker of hip fracture risk--The Study of Osteoporotic Fractures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jul 1999
Cauley J A, Zmuda J M, Yaffe K, Kuller L H, Ferrell R E, Wisniewski S R, Cummings S R
Abstract excerpt
Hip fractures are common and devastating events. The apolipoprotein E*4 (APOE) allele, associated with Alzheimer's disease, has also been associated with osteoporosis in hemodialysis patients. We prospectively studied 1750 women, age >/=65 years, who underwent measurements of hip and calcaneal bone mineral density (BMD), were typed for APOE and followed for approximately 7.0 years for the occurrence of fractures...
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