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Article

Methylthioadenosine (MTA) inhibits melanoma cell proliferation and in vivo tumor growth.

BMC cancer - 8 Jun 2010

Andreu-Pérez Pedro, Hernandez-Losa Javier, Moliné Teresa, Gil Rosa, Grueso Judit, Pujol Anna, Cortés Javier, Avila Matias A, Recio Juan A

Abstract excerpt

BACKGROUND: Melanoma is the most deadly form of skin cancer without effective treatment. Methylthioadenosine (MTA) is a naturally occurring nucleoside with differential effects on normal and transformed cells. MTA has been widely demonstrated to promote anti-proliferative and pro-apoptotic respon...

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Source

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Identifiers

PMID: 20529342
DOI: 10.1186/1471-2407-10-265
PMCID: PMC2891639

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20529342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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