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Article

Common variants in FOXP1 are associated with generalized vitiligo.

Nature genetics - 1 Jul 2010

Jin Ying, Birlea Stanca A, Fain Pamela R, Mailloux Christina M, Riccardi Sheri L, Gowan Katherine, Holland Paulene J, Bennett Dorothy C, Wallace Margaret R, McCormack Wayne T, Kemp E Helen, Gawkrodger David J, Weetman Anthony P, Picardo Mauro, Leone Giovanni, Taïeb Alain, Jouary Thomas, Ezzedine Khaled, van Geel Nanny, Lambert Jo, Overbeck Andreas, Spritz Richard A

Abstract excerpt

In a recent genome-wide association study of generalized vitiligo, we identified ten confirmed susceptibility loci. By testing additional loci that showed suggestive association in the genome-wide study, using two replication cohorts of European descent, we observed replicated association of gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20526340
DOI: 10.1038/ng.602
PMCID: PMC2893242

Genes

FOXP1
CCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20526340-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Common variants in FOXP1 are associated with generalized vitiligo.PMID 20526340Read ↗

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Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.Semantic proximity Read ↗

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.Semantic proximity Read ↗

Association between FOXP3 polymorphisms and vitiligo in a Han Chinese population.Semantic proximity Read ↗

Association of FOXP3 (rs3761548) promoter polymorphism with nondermatomal vitiligo: A study from India.Semantic proximity Read ↗

Association of FOXP3 and GAGE10 promoter polymorphisms and decreased FOXP3 expression in regulatory T cells with susceptibility to generalized vitiligo in Gujarat population.Semantic proximity Read ↗

Altered expression of nuclear factor of activated T cells, forkhead box P3, and immune-suppressive genes in regulatory T cells of generalized vitiligo patients.Semantic proximity Read ↗

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