Article
Intercohort gene expression co-analysis reveals chemokine receptors as prognostic indicators in Ewing's sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2010
Bennani-Baiti Idriss M, Cooper Aaron, Lawlor Elizabeth R, Kauer Maximilian, Ban Jozef, Aryee Dave N T, Kovar Heinrich
Abstract excerpt
PURPOSE: We report a novel analytic method, named intercohort co-analysis or Ican, which aids in the discovery of genes with predictive value for the progression or outcome of diseases from small-size cohorts. We tested this premise in Ewing's sarcoma (ES), a highly metastatic cancer of bone and soft tissues that lacks validated molecular metastasis and prognostic indicators. EXPERIMENTAL DESIGN: To uncover genes...
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