Article
Do GST polymorphisms influence in the pathogenesis of diabetic nephropathy?
Molecular and cellular endocrinology - 15 Dec 2018
de Lima Rayane Mendes, Dos Anjos Laura Raniere Borges, Alves Thales Biffe, Coelho Alexandre Siqueira Guedes, Pedrino Gustavo Rodrigues, da Silva Santos Rodrigo, da Silva Cruz Aline Helena, da Silva Reis Angela Adamski
Abstract excerpt
Diabetic patients often develop Diabetic Nephropathy (DN) despite severe long-lasting hyperglycemia, while others develop DN even under intensive insulin therapy. This indicates that factors other than chronic hyperglycemia may also contribute to the susceptibility to the development of DN. The purpose of this case-control study was to investigate the possible role of GSTM1 and GSTT1 deletion polymorphisms, and...
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