Article
CCR5, RANTES and SDF-1 polymorphisms and mother-to-child HIV-1 transmission.
International journal of immunogenetics - 1 Aug 2010
Katz D A, John-Stewart G C, Richardson B A, Majiwa M, Mabuka J M, Lohman-Payne B, Farquhar C
Abstract excerpt
Summary Among 288 HIV-1-infected, breastfeeding women who received zidovudine prophylaxis and were followed with their infants in Nairobi, we found no associations between maternal genetic polymorphisms in CCR5 (59029G/A, 59353T/C, 59356T/C, 59402G/A), RANTES (-403G/A) and SDF-1 (3'801G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations.
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