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Gene Correction in Human Embryonic and Induced Pluripotent Stem Cells: Promises and Challenges Ahead

1 Jun 2010

Abstract excerpt

The sequencing of the human genome has greatly facilitated our ability to identify the gene candidates that are critical for developmental regulation and disease progression. However, investigators seeking to use such data to gain a better understanding of the developmental biology and therapeutic potential of pluripotent stem cell types may be frustrated by the limitations of current genetic engineering...

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PMID: 20514030
DOI: 10.1038/mt.2010.92

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