Article
Decoded calreticulin-deficient embryonic stem cell transcriptome resolves latent cardiophenotype.
Stem cells (Dayton, Ohio) - 1 Jul 2010
Faustino Randolph S, Chiriac Anca, Niederlander Nicolas J, Nelson Timothy J, Behfar Atta, Mishra Prasanna K, Macura Slobodan, Michalak Marek, Terzic Andre, Perez-Terzic Carmen
Abstract excerpt
Genomic perturbations that challenge normal signaling at the pluripotent stage may trigger unforeseen ontogenic aberrancies. Anticipatory systems biology identification of transcriptome landscapes that underlie latent phenotypes would offer molecular diagnosis before the onset of symptoms. The pu...
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