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Article

Influence of M. tuberculosis Lineage Variability within a Clinical Trial for Pulmonary Tuberculosis

20 May 2010

Abstract excerpt

Recent studies suggest that M. tuberculosis lineage and host genetics interact to impact how active tuberculosis presents clinically. We determined the phylogenetic lineages of M. tuberculosis isolates from participants enrolled in the Tuberculosis Trials Consortium Study 28, conducted in Brazil, Canada, South Africa, Spain, Uganda and the United States, and secondarily explored the relationship between lineage,...

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Identifiers

PMID: 20505778
DOI: 10.1371/journal.pone.0010753

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