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Ovarian follicle loss in humans and mice: lessons from statistical model comparison

26 May 2010

Abstract excerpt

BACKGROUND: Mammalian oocyte stocks reach maximum size in early development and begin depletion immediately thereafter. This depletion ends women's fertility by midlife. Here we compare five models proposed to characterize human follicular depletion, highlight underlying variation in atresia, and use oocyte counts from laboratory mice to illustrate possible effects of known covariates. METHODS: We compared...

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PMID: 20504871
DOI: 10.1093/humrep/deq136

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