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Mathematical recapitulation of the end stages of human ovarian aging

12 Jan 2024

Abstract excerpt

Ovarian aging in women can be described as highly unpredictable within individuals but predictable across large populations. We showed previously that modeling an individual woman's ovarian reserve of primordial follicles using mathematical random walks replicates the natural pattern of growing follicles exiting the reserve. Compiling many simulations yields the observed population distribution of the age at...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 38215196
DOI: 10.1126/sciadv.adj4490

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