Article
Expression patterns of the Wtx/Amer gene family during mouse embryonic development.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2010
Comai Glenda, Boutet Agnes, Neirijnck Yasmine, Schedl Andreas
Abstract excerpt
WTX/AMER1 is a novel negative regulator of the WNT/beta-catenin pathway with mutations detected in Wilms' tumors and an X-linked sclerosing bone dysplasia. WTX/AMER1 (Fam123b) shares several domains of homology with two other recently identified proteins: AMER2 (Fam123a) and AMER3 (Fam123c). Here, we describe an in-depth expression analysis of all three members of this gene family during mouse embryonic...
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