Article
VARS2 V552V variant as prognostic marker in patients with early breast cancer.
Medical oncology (Northwood, London, England) - 1 Dec 2011
Chae Yee Soo, Lee Soo Jung, Moon Joon Ho, Kang Byung Woog, Kim Jong Gwang, Sohn Sang Kyun, Jung Jin Hyang, Park Ho Yong, Park Ji Young, Kim Hye Jung, Lee Sang-Woo
Abstract excerpt
The present study analyzed the polymorphisms of DNA repair genes and their impact on the survival of 240 patients with early breast cancer. The genomic DNA was extracted from paraffin-embedded tumor-free tissue or blood, and thirteen polymorphisms in 12 DNA repair genes were determined using the Sequenom Mass array system. Among the target polymorphisms, VARS2 rs2074511 and POLE rs5744857 were found to correlate...
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