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Chromatic pupillometry dissects function of the three different light-sensitive retinal cell populations in RPE65 deficiency.

Investigative ophthalmology & visual science - 17 Aug 2012

Lorenz Birgit, Strohmayr Elisabeth, Zahn Steffen, Friedburg Christoph, Kramer Martin, Preising Markus, Stieger Knut

Abstract excerpt

PURPOSE: The aim of the study was to objectively characterize the function of rods, cones, and intrinsic photosensitive retinal ganglion cells (ipRGCs) in patients with RPE65 mutations by using two published protocols for chromatic pupillometry, and to correlate the data with the clinical phenotype. METHODS: The study group comprised 11 patients with RPE65 mutations, and for control purposes, 32 healthy probands...

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cis-trans-Isomerases
Color Vision Defects
Photic Stimulation
Retinal Cone Photoreceptor Cells
Retinal Ganglion Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Retinal Rod Photoreceptor Cells

Visual Field Tests

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Identifiers

PMID: 22807296
DOI: 10.1167/iovs.12-9974

Genes

RPE65
FST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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