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Pupillary Light Reflex Reveals Melanopsin System Alteration in the Background of Myopia-26, the Female Limited Form of Early-Onset High Myopia.

Investigative ophthalmology & visual science - 1 Jul 2024

Barboni Mirella T S, Széll Noémi, Sohajda Zoltán, Fehér Tamás

Abstract excerpt

Purpose: The purpose of this study was to evaluate pupillary light reflex (PLR) to chromatic flashes in patients with early-onset high-myopia (eoHM) without (myopic controls = M-CTRL) and with (female-limited myopia-26 = MYP-26) genetic mutations in the ARR3 gene encoding the cone arrestin. Methods: Participants were 26 female subjects divided into 3 groups: emmetropic controls (E-CTRL, N = 12, mean age = 28.6 ±...

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Arrestin
Dark Adaptation
Light
Myopia
Myopia, Degenerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Photic Stimulation

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Identifiers

PMID: 38958970
DOI: 10.1167/iovs.65.8.6
PMCID: PMC11223624

Genes

ARR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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