Article
Dietary-induced serum phenolic acids promote bone growth via p38 MAPK/β-catenin canonical Wnt signaling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2010
Chen Jin-Ran, Lazarenko Oxana P, Wu Xianli, Kang Jie, Blackburn Michael L, Shankar Kartik, Badger Thomas M, Ronis Martin J J
Abstract excerpt
Diet and nutritional status are critical factors that influences bone development. In this report we demonstrate that a mixture of phenolic acids found in the serum of young rats fed blueberries (BB) significantly stimulated osteoblast differentiation, resulting in significantly increased bone mass. Greater bone formation in BB diet-fed animals was associated with increases in osteoblast progenitors and...
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