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Article

A common variant in pre-miR-146 is associated with coronary artery disease risk and its mature miRNA expression.

Mutation research - 1 Mar 2014

Xiong Xing-dong, Cho Miook, Cai Xiu-ping, Cheng Jie, Jing Xia, Cen Jin-ming, Liu Xinguang, Yang Xi-li, Suh Yousin

Abstract excerpt

miRNAs are small non-coding RNAs that play an important role in numerous physiological processes. Common single nucleotide polymorphisms (SNPs) in pre-miRNAs may change their property through altering miRNAs expression and/or maturation, resulting in diverse functional consequences. To date, the role of genetic variants in pre-miRNAs on coronary artery disease (CAD) risk remains poorly understood. Here we aimed...

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Identifiers

PMID: 24447667
DOI: 10.1016/j.mrfmmm.2014.01.001

Genes

CAD

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