Article
Correlation of miR-146a-5p plasma levels and rs2910164 polymorphism with left ventricle outflow tract obstruction in hypertrophic cardiomyopathy.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese - 1 Jan 2000
Ntelios Dimitrios, Efthimiadis Georgios, Zegkos Thomas, Didagelos Matthaios, Katopodi Theodora, Meditskou Soultana, Parcharidou Despoina, Karvounis Haralampos, Tzimagiorgis Georgios
Abstract excerpt
OBJECTIVE: Hypertrophic cardiomyopathy (HCM) is a genetic disease of the myocardium that is characterized by phenotypic variability among patients. miR-146a is a small non-coding RNA that is well known for its role in inflammation and myocardial hypertrophy. The aim of this study is to evaluate the role of miR-146a as a candidate genetic factor influencing HCM phenotype. METHODS: In this study, 140 HCM patients...
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