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Quantitative Proteomic Profiling Studies of Pancreatic Cancer Stem Cells

21 May 2010

Abstract excerpt

Analyzing subpopulations of tumor cells in tissue is a challenging subject in proteomic studies. Pancreatic cancer stem cells (CSCs) are such a group of cells that only constitute 0.2-0.8% of the total tumor cells but have been found to be the origin of pancreatic cancer carcinogenesis and metastasis. Global proteome profiling of pancreatic CSCs from xenograft tumors in mice is a promising way to unveil the...

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PMID: 20486718
DOI: 10.1021/pr100231m

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