Article
Rhinovirus genome evolution during experimental human infection.
PloS one - 11 May 2010
Cordey Samuel, Junier Thomas, Gerlach Daniel, Gobbini Francesca, Farinelli Laurent, Zdobnov Evgeny M, Winther Birgit, Tapparel Caroline, Kaiser Laurent
Abstract excerpt
Human rhinoviruses (HRVs) evolve rapidly due in part to their error-prone RNA polymerase. Knowledge of the diversity of HRV populations emerging during the course of a natural infection is essential and represents a basis for the design of future potential vaccines and antiviral drugs. To evaluat...
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