Article
Genome-wide diversity and selective pressure in the human rhinovirus.
Virology journal - 3 May 2007
Kistler Amy L, Webster Dale R, Rouskin Silvi, Magrini Vince, Credle Joel J, Schnurr David P, Boushey Homer A, Mardis Elaine R, Li Hao, DeRisi Joseph L
Abstract excerpt
BACKGROUND: The human rhinoviruses (HRV) are one of the most common and diverse respiratory pathogens of humans. Over 100 distinct HRV serotypes are known, yet only 6 genomes are available. Due to the paucity of HRV genome sequence, little is known about the genetic diversity within HRV or the forces driving this diversity. Previous comparative genome sequence analyses indicate that recombination drives...
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