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Article

Comparison of genome-wide variation between Malawians and African ancestry HapMap populations.

Journal of human genetics - 1 Jun 2010

Joubert Bonnie R, North Kari E, Wang Yunfei, Mwapasa Victor, Franceschini Nora, Meshnick Steven R, Lange Ethan M

Abstract excerpt

Understanding genetic variation between populations is important because it affects the portability of human genome-wide analytical methods. We compared genetic variation and substructure between Malawians and other African and non-African HapMap populations. Allele frequencies and adjacent linkage disequilibrium (LD) were measured for 617 715 single nucleotide polymorphisms (SNPs) across subject genomes. Allele...

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PMID: 20485449
DOI: 10.1038/jhg.2010.41
PMCID: PMC2909738

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