Article

DNA methylation biomarker selected by an ensemble machine learning approach predicts mortality risk in an HIV-positive veteran population

2019-10-29

Abstract excerpt

<h4>Background</h4> With the improved life expectancy of people living with HIV (PLWH), identifying vulnerable subpopulations at high risk of mortality is important for clinical care. Evidences showed that DNA methylation (DNAm) is associated with aging and mortality in non-HIV populations. Here, we aimed to establish a panel of DNAm biomarkers that can predict mortality risk among PLWH. <h4>Methods</h4> 1,081 HIV...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e7cc583b-5819-50df-b8a0-fda9816b34aa
DOI: 10.1101/19010272

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DNA methylation biomarker selected by an ensemble machine learning approach predicts mortality risk in an HIV-positive veteran populationDOI 10.1101/19010272Read

DNA methylation biomarker selected by an ensemble machine learning approach predicts mortality risk in an HIV-positive veteran populationSemantic proximity Read

Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortalitySemantic proximity Read

DNA methylation‐based telomere length is associated with HIV infection, physical frailty, cancer, and all‐cause mortalitySemantic proximity Read

Identification of HIV infection-related DNA methylation sites and advanced epigenetic aging in HIV-positive, treatment-naive U.S. veteransSemantic proximity Read

Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA.Semantic proximity Read

Occurrence of Accelerated Epigenetic Aging and Methylation Disruptions in Human Immunodeficiency Virus Infection Before Antiretroviral TherapySemantic proximity Read

DNA Methylation Markers of Type 2 Diabetes Mellitus Among Male Veterans With or Without Human Immunodeficiency Virus InfectionSemantic proximity Read

Epigenetics, HIV, and Cardiovascular Disease Risk.Semantic proximity Read

Epigenetic Age Acceleration Markers Are Associated With Physiologic Frailty and All-Cause Mortality in People With Human Immunodeficiency VirusSemantic proximity Read

Sex differences in epigenetic ageing for older people living with HIVSemantic proximity Read

DNA methylation mediates the effect of cocaine use on HIV severitySemantic proximity Read

Deciphering DNA Methylation in HIV InfectionSemantic proximity Read