Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms and regulation of the gene-expression response to sepsis.

Pediatrics - 1 Jun 2010

Cornell Timothy T, Wynn James, Shanley Thomas P, Wheeler Derek S, Wong Hector R

Abstract excerpt

Sepsis is defined as the systemic inflammatory response of the human host that is triggered by an invading pathogen. Despite tremendous advances in both our knowledge of and treatment strategies for this syndrome, sepsis remains among the major causes of morbidity and mortality in children worldw...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenesis, Genetic
Share to Gene Expression
Share to Immune Response and Inflammation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Sensitivity and Specificity

Share to Sepsis

Share to Shock, Septic

Share to Toll-Like Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 20478944
DOI: 10.1542/peds.2009-3274
PMCID: PMC2892227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20478944-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms and regulation of the gene-expression response to sepsis.PMID 20478944Read ↗

Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patientsSemantic proximity Read ↗

Differential gene expression analysis reveals novel genes and pathways in pediatric septic shock patientsSemantic proximity Read ↗

The Epigenetics of Sepsis: How Gene Modulation Shapes OutcomesSemantic proximity Read ↗

Integration of Mendelian Randomization to Explore the Genetic Influences of Pediatric Sepsis: A Focus on RGL4, ATP9A, MAP3K7CL, and DDX11L2Semantic proximity Read ↗

Genome-wide association study of pediatric bacteremia and sepsisSemantic proximity Read ↗

Sepsis, immunosuppression and the role of epigenetic mechanismsSemantic proximity Read ↗

Screening of Key Genes of Sepsis and Septic Shock Using Bioinformatics AnalysisSemantic proximity Read ↗

Age-related stress gene expression in neonatal sepsis involves regulatory networks and immune cell infiltrationSemantic proximity Read ↗

Altered miRNAs Expression Profiles and Modulation of Immune Response Genes and Proteins During Neonatal SepsisSemantic proximity Read ↗

Landscape of multiple tissues' gene expression pattern associated with severe sepsis: Genetic insights from Mendelian randomization and trans-omics analysis.Semantic proximity Read ↗

Genetic insights into sepsis: what have we learned and how will it help?Semantic proximity Read ↗

Unique transcriptomic response to sepsis is observed among patients of different age groupsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.