Article
Hypermethylation of the Ras association domain family 1A (RASSF1A) gene in gallbladder cancer.
Molecules and cells - 31 Dec 2007
Kee Se Kook, Lee Ji Yun, Kim Mi Jin, Lee Su Man, Jung Young Won, Kim Young Joo, Park Jae Yong, Bae Han Ik, Hong Hae Sook, Yun Young Kook, Kim Sang Geol, Kim Dong Sun
Abstract excerpt
The tumor suppressor gene Ras association domain family 1A (RASSF1A) is highly methylated in a wide range of human sporadic tumors. The current study investigated the hypermethylation of RASSF1A, the expression of RASSF1A protein, and the correlation between these and the clinicopathological features of gallbladder (GB) cancer in Korean patients. Formalin-fixed, paraffin-embedded tumors and non-neoplastic GB...
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