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Article

The Arsenic Exposure Hypothesis for Alzheimer Disease

14 May 2010

Abstract excerpt

Prior research has shown that arsenic exposure induces changes that coincide with most of the developmental, biochemical, pathologic, and clinical features of Alzheimer disease (AD) and associated disorders. On the basis of this literature, we propose the Arsenic Exposure Hypothesis for AD that is inclusive of and cooperative with the existing hypotheses. Arsenic toxicity induces hyperphosphorylation of protein...

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PMID: 20473132
DOI: 10.1097/wad.0b013e3181d71bc7

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