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Article

Diagnosing cellular defects in an unexplained case of total fertilization failure

15 May 2010

Abstract excerpt

Despite the advent of ICSI, cases of total fertilization failure (TFF) often lead to cycle cancellation with limited diagnostic and therapeutic strategies currently available. We report on the case of an infertile couple who failed to conceive after repeated IVF and ICSI. Sperm of the husband were morphologically normal and passed a functional test assessing their ability to activate mouse oocytes. Whether...

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PMID: 20472911
DOI: 10.1093/humrep/deq064

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