Article
Variant in CD209 promoter is associated with severity of liver disease in chronic hepatitis C virus infection.
Human immunology - 1 Aug 2010
Ryan Elizabeth J, Dring Megan, Ryan Cliona M, McNulty Carol, Stevenson Nigel J, Lawless Matthew W, Crowe John, Nolan Niamh, Hegarty John E, O'Farrelly Cliona
Abstract excerpt
CD209, a c-type lectin expressed by dendritic cells (DCs), acts as a pathogen recognition receptor. A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever. Because CD20...
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