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Article

How old is this mutation? - a study of three Ashkenazi Jewish founder mutations.

BMC genetics - 14 May 2010

Greenwood Celia M T, Sun Shuying, Veenstra Justin, Hamel Nancy, Niell Bethany, Gruber Stephen, Foulkes William D

Abstract excerpt

BACKGROUND: Several founder mutations leading to increased risk of cancer among Ashkenazi Jewish individuals have been identified, and some estimates of the age of the mutations have been published. A variety of different methods have been used previously to estimate the age of the mutations. Here three datasets containing genotype information near known founder mutations are reanalyzed in order to compare three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20470408
DOI: 10.1186/1471-2156-11-39
PMCID: PMC2889843

Genes

MSH2
APC
BRCA2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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