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Article

Heritability of abnormalities in cardiopulmonary coupling in sleep apnea: use of an electrocardiogram-based technique.

Sleep - 1 May 2010

Ibrahim Lamia H, Jacono Frank J, Patel Sanjay R, Thomas Robert J, Larkin Emma K, Mietus Joseph E, Peng Chung-Kang, Goldberger Ary L, Redline Susan

Abstract excerpt

RATIONALE: Studies of the genetics of obstructive sleep apnea may be facilitated by identifying intermediate traits with high heritability that quantify etiological pathways, such as those related to respiratory control. Electrocardiogram (ECG)-based sleep spectrograms, measuring the coupling between respiratory modulation of ECG QRS-wave amplitude and heart rate variability, may provide measures of sleep state...

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Source

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Identifiers

PMID: 20469806
DOI: 10.1093/sleep/33.5.643
PMCID: PMC2864879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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