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Article

Loss of Dicer in Sertoli Cells Has a Major Impact on the Testicular Proteome of Mice

13 May 2010

Abstract excerpt

Sertoli cells (SCs) are the central, essential coordinators of spermatogenesis, without which germ cell development cannot occur. We previously showed that Dicer, an RNaseIII endonuclease required for microRNA (miRNA) biogenesis, is absolutely essential for Sertoli cells to mature, survive, and ultimately sustain germ cell development. Here, using isotope-coded protein labeling, a technique for protein relative...

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PMID: 20467044
DOI: 10.1074/mcp.m900587-mcp200

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Loss of Dicer in Sertoli Cells Has a Major Impact on the Testicular Proteome of MicePMID 20467044Read ↗

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Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse TestisSemantic proximity Read ↗

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