Article
Characterization of the novel, pediatric Hodgkin disease-derived cell line HKB-1.
Medical and pediatric oncology - 1 Sept 1998
Wagner H J, Klintworth F, Jabs W, Lange K, Schlegelberger B, Harder L, Feller A C, Bucsky P
Abstract excerpt
BACKGROUND: A novel Hodgkin disease (HD)-derived cell line, designated HKB-1, was established from pulmonary HD of nodular sclerosing subtype of a 14-year-old-girl. PROCEDURE AND RESULTS: Immunophenotypically, HKB-1 cells are of B cell in phenotype, being also positive for markers CD15, CD25 and CD30. Transformation of the cell line by Epstein-Barr virus (EBV) was excluded by failure to detect EBV antigens and...
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