Article
Digital quantification of human eye color highlights genetic association of three new loci.
PLoS genetics - 6 May 2010
Liu Fan, Wollstein Andreas, Hysi Pirro G, Ankra-Badu Georgina A, Spector Timothy D, Park Daniel, Zhu Gu, Larsson Mats, Duffy David L, Montgomery Grant W, Mackey David A, Walsh Susan, Lao Oscar, Hofman Albert, Rivadeneira Fernando, Vingerling Johannes R, Uitterlinden André G, Martin Nicholas G, Hammond Christopher J, Kayser Manfred
Abstract excerpt
Previous studies have successfully identified genetic variants in several genes associated with human iris (eye) color; however, they all used simplified categorical trait information. Here, we quantified continuous eye color variation into hue and saturation values using high-resolution digital full-eye photographs and conducted a genome-wide association study on 5,951 Dutch Europeans from the Rotterdam Study....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.