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Article

Importance of nonsynonymous OCA 2 variants in human eye color prediction

11 Mar 2016

Abstract excerpt

BACKGROUND: The color of the eyes is one of the most prominent phenotypes in humans and it is often used to describe the appearance of an individual. The intensity of pigmentation in the iris is strongly associated with one single-nucleotide polymorphism (SNP), rs12913832:A>G that is located in the promotor region of OCA2 (OMIM #611409). Nevertheless, many eye colors cannot be explained by only considering...

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PMID: 27468418
DOI: 10.1002/mgg3.213

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