Article
Future nutrigenetics: in search of the missing genetic variation.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2009
Mariman Edwin C M
Abstract excerpt
Despite considerable effort, genetic analysis of complex disorders and traits, including those related to nutrition, has revealed only a very small part of the expected genetic variation. Missing variation may occur as conditional variation depending on the presence of defined lifestyle factors, as epigenetic variation or as low-moderate effect size variation not detected by mutation screening and genome-wide...
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