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Article

Genetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice.

Clinical immunology (Orlando, Fla.) - 1 Aug 2010

Sharma Rahul, Ju Shyr-Te

Abstract excerpt

IPEX (Immunodysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome is a rare, recessive disorder in patients with mutations in the foxp3 gene, the normal expression of which is required for the generation of functional regulatory T-cells. Scurfy mice also bear a mutation in the foxp3,...

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Identifiers

PMID: 20452830
DOI: 10.1016/j.clim.2010.04.004
PMCID: PMC2916692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20452830-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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