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Article

Analysis of gene amplification in head‐and‐neck squamous‐cell carcinomas

19 Jun 1991

Abstract excerpt

The presence of gene amplification was determined in 66 fresh head-and-neck SCC specimens using a battery of 9 different probes. Amplification of at least one gene was found in 12 samples (18%), of which 7 were amplified at multiple loci (58%). We observed amplifications for EGFR (10% of samples) and c-myc (9%), as well as co-amplification of bcl-1/int-2 (7%). No amplifications were demonstrated for c-Ha-ras-1,...

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PMID: 2045198
DOI: 10.1002/ijc.2910480406

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Source receipt: pubmed, retrieved 7 Sept 2026.

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