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Article

Accumulation of caveolin-3 protein is limited in damaged muscle in chicken muscular dystrophy.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology - 1 Sept 2010

Matsumoto Hirokazu, Sasazaki Shinji, Fujiwara Akira, Ichihara Nobutsune, Kikuchi Tateki, Mannen Hideyuki

Abstract excerpt

Members of the caveolin family are the main component of caveolae, and caveolin-3 is a muscle-specific protein. Caveolin-3 deficiency induces a muscular dystrophic phenotype, while its overexpression is also harmful to muscle cells. Increased caveolae were observed in chicken muscular dystrophy; however, the underlying mechanism causing the onset remains unclear. Therefore, the current study analyzes the...

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Caveolin 3
Chickens
Muscle, Skeletal
Muscular Dystrophies
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reverse Transcriptase Polymerase Chain Reaction

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PMID: 20451648
DOI: 10.1016/j.cbpa.2010.04.019

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