Article
Chromosomal mapping of glutamate dehydrogenase gene sequences to mouse chromosomes 7 and 14.
Genomics - 1 May 1991
Tzimagiorgis G, Adamson M C, Kozak C A, Moschonas N K
Abstract excerpt
Glutamate dehydrogenase (GLUD) plays an important role in mammalian neuronal transmission. In human, GLUD is encoded by a small gene family. To determine whether defects in Glud genes are associated with known neurological mutations in the mouse and to contribute to the comparative mapping of homologous genes in man and mouse, the chromosomal location of genes reactive with a mouse brain GLUD cDNA were...
Topics
- Animals
- Base Sequence
- Blotting, Southern
- Chromosome Mapping
- Crosses, Genetic
- Genetic Linkage
- Glutamate Dehydrogenase
- Mice
- Multigene Family
- Mutation
